متالوتیونئین ۱ای

MT1A
معین‌کننده‌ها
نام‌های دیگر	MT1A, MT1, MT1S, MTC, Metallothionein 1A, MT-1A, MT-IA
شناسه‌های بیرونی	OMIM: 156350 GeneCards: MT1A
هستی‌شناسی ژن عملکرد ملکولی • zinc ion binding • GO:0001948، GO:0016582 پیوند پروتئینی • metal ion binding ترکیبات سلولی • سیتوپلاسم • perinuclear region of cytoplasm • سیتوزول • هسته یاخته فرایند زیستی • response to metal ion • negative regulation of growth • cellular response to cadmium ion • cellular response to zinc ion • cellular zinc ion homeostasis • detoxification of copper ion • cellular response to copper ion منابع: آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
گونه‌ها	انسان	موش
Entrez	4489	ن/م
آنسامبل	ENSG00000205362	ن/م
یونی‌پروت	P04731	ن/م
RefSeq (mRNA)	NM_005946	ن/م
RefSeq (پروتئین)	NP_005937	ن/م
موقعیت (UCSC)	ن/م	ن/م
جستجوی PubMed		ن/م
ویکی‌داده
مشاهده/ویرایش انسان

متالوتیونئین ۱ای پروتئینی است که در انسان توسط ژن MT1A کدگذاری می‌شود.

مطالعه بیشتر

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• Campagne MV, Thibodeaux H, van Bruggen N, et al. (2000). "Increased binding activity at an antioxidant-responsive element in the metallothionein-1 promoter and rapid induction of metallothionein-1 and -2 in response to cerebral ischemia and reperfusion". J. Neurosci. 20 (14): 5200–7. doi:10.1523/JNEUROSCI.20-14-05200.2000. PMC 6772313. PMID 10884303.
• Rahman MT, De Ley M (2001). "Metallothionein isogene transcription in red blood cell precursors from human cord blood". Eur. J. Biochem. 268 (3): 849–56. doi:10.1046/j.1432-1327.2001.01947.x. PMID 11168427.
• Levadoux-Martin M, Hesketh JE, Beattie JH, Wallace HM (2001). "Influence of metallothionein-1 localization on its function". Biochem. J. 355 (Pt 2): 473–9. doi:10.1042/0264-6021:3550473. PMC 1221760. PMID 11284736.
• Richarz AN, Brätter P (2002). "Speciation analysis of trace elements in the brains of individuals with Alzheimer's disease with special emphasis on metallothioneins". Analytical and Bioanalytical Chemistry. 372 (3): 412–7. doi:10.1007/s00216-001-1187-5. PMID 11939525. S2CID 21611530.
• Minami T, Kubo K, Ichida S (2003). "Determination of metallothionein-1/metallothionein-2 ratios in the mouse liver and pancreas by capillary zone electrophoresis using a polyacrylamide-coated capillary at neutral pH". J. Chromatogr. B. 779 (2): 211–9. doi:10.1016/S1570-0232(02)00375-6. PMID 12361735.