لاکتات دهیدروژناز A

LDHA
ساختارهای موجود
PDB	جستجوی هم‌ساخت‌شناسی: PDBe RCSB
فهرست شناسه‌های PDB
	1I10, 4AJP, 4JNK, 4L4R, 4L4S, 4M49, 4OJN, 4OKN, 4QO7, 4QO8, 4QSM, 4QT0, 4R68, 4R69, 4RLS, 4ZVV
معین‌کننده‌ها
نام‌های دیگر	LDHA, GSD11, HEL-S-133P, LDH1, LDHM, PIG19, lactate dehydrogenase A
شناسه‌های بیرونی	OMIM: 150000 MGI: 96759 HomoloGene: 56495 GeneCards: LDHA
موقعیت ژن (موش)
کروموزوم	کروموزوم ۷ (موش)
پایان	46,505,051 bp
الگوی گسترش RNA
	More reference expression data
هستی‌شناسی ژن
عملکرد ملکولی	• GO:0050229 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; • NAD binding; • lactate dehydrogenase activity; • kinase binding; • GO:0001948، GO:0016582 پیوند پروتئینی; • catalytic activity; • identical protein binding; • oxidoreductase activity; • L-lactate dehydrogenase activity; • cadherin binding;
ترکیبات سلولی	• سیتوپلاسم; • membrane; • extracellular exosome; • هسته یاخته; • سیتوزول;
فرایند زیستی	• post-embryonic animal organ development; • lactate metabolic process; • response to hypoxia; • قندکافت; • GO:1904578 response to organic cyclic compound; • substantia nigra development; • response to nutrient; • carboxylic acid metabolic process; • response to glucose; • NAD metabolic process; • response to estrogen; • pyruvate metabolic process; • positive regulation of apoptotic process; • response to cAMP; • response to hydrogen peroxide; • سوخت‌وساز کربوهیدرات;
	منابع: آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
	3939
	16828
	ENSG00000134333; ENSG00000288299
	ENSMUSG00000063229
	P00338
	P06151
	NM_001135239، NM_001165414، NM_001165415، NM_001165416، NM_005566 NR_028500، NM_001135239، NM_001165414، NM_001165415، NM_001165416، NM_005566
	NM_010699، NR_102727، XM_030242176 NM_001136069، NM_010699، NR_102727، XM_030242176
	NP_001158886، NP_001158887، NP_001158888، NP_005557 NP_001128711، NP_001158886، NP_001158887، NP_001158888، NP_005557
	NP_034829، XP_030098036 NP_001129541، NP_034829، XP_030098036
	ویکی‌داده
مشاهده/ویرایش انسان	مشاهده/ویرایش موش

لاکتات دهیدروژناز A (انگلیسی: Lactate dehydrogenase A) یک آنزیم است که در انسان توسط ژن «LDHA» کدگذاری می‌شود^[۴] و یکی از مونومرهای لاکتات دهیدروژناز که خود نوعی آنزیم تترامر (چهار زنجیره‌ای) است. زیرواحدِ دیگر لاکتات دهیدروژناز، لاکتات دهیدروژناز B نام دارد.

منابع

↑ ^۱٫۰ ^۱٫۱ ^۱٫۲ GRCm38: Ensembl release 89: ENSMUSG00000063229 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Chung FZ, Tsujibo H, Bhattacharyya U, Sharief FS, Li SS (November 1985). "Genomic organization of human lactate dehydrogenase-A gene". Biochemical Journal. 231 (3): 537–41. PMC 1152784. PMID 3000353.

مشارکت‌کنندگان ویکی‌پدیا. «Lactate dehydrogenase A». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۲۰ اکتبر ۲۰۱۸.

بیشتر بخوانید

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