الگو:PBB/10013

Histone deacetylase 6
Rendering based on بانک داده پروتئین 3C5K.
ساختارهای موجود بانک داده پروتئین Ortholog search: PDBe, RCSB فهرست کدهای شناسه PDB 3C5K, 3GV4, 3PHD
شاخص‌ها
نماد ژن	HDAC6; HD6
شناسه‌های بیرونی	OMIM: 300272 MGI: 1333752 HomoloGene: 31353 ChEMBL: 1865 GeneCards: HDAC6 Gene
EC number	3.5.1.98
هستی‌شناسی ژن Molecular function • actin binding • histone deacetylase activity • protein binding • beta-catenin binding • microtubule binding • zinc ion binding • enzyme binding • polyubiquitin binding • NAD-dependent histone deacetylase activity (H3-K14 specific) • histone deacetylase binding • tubulin deacetylase activity • alpha-tubulin binding • NAD-dependent histone deacetylase activity (H3-K9 specific) • NAD-dependent histone deacetylase activity (H4-K16 specific) • tau protein binding • beta-tubulin binding • Hsp90 protein binding • dynein complex binding • NAD-dependent histone deacetylase activity (H3-K18 specific) Cellular component • histone deacetylase complex • nucleus • nucleolus • cytoplasm • cytosol • microtubule • microtubule associated complex • cytoplasmic microtubule • caveola • inclusion body • aggresome • dynein complex • cell leading edge • perinuclear region of cytoplasm Biological process • protein polyubiquitination • transcription, DNA-dependent • protein deacetylation • misfolded or incompletely synthesized protein catabolic process • intracellular protein transport • negative regulation of microtubule depolymerization • response to toxin • positive regulation of signal transduction • response to organic substance • regulation of receptor activity • positive regulation of epithelial cell migration • negative regulation of hydrogen peroxide metabolic process • positive regulation of receptor biosynthetic process • macroautophagy • histone deacetylation • lysosome localization • peptidyl-lysine deacetylation • cellular response to topologically incorrect protein • positive regulation of apoptotic process • ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway • protein complex disassembly • negative regulation of protein complex disassembly • negative regulation of proteolysis • negative regulation of transcription, DNA-dependent • negative regulation of oxidoreductase activity • response to misfolded protein • regulation of microtubule-based movement • regulation of androgen receptor signaling pathway • cellular response to hydrogen peroxide • aggresome assembly • polyubiquitinated misfolded protein transport • Hsp90 deacetylation • response to growth factor stimulus • cellular response to misfolded protein • positive regulation of chaperone-mediated protein complex assembly • tubulin deacetylation Sources: Amigo / QuickGO
الگوی بیان RNA
دادهای بیان مرجع بیشتر
اورتولوگ
گونه‌ها	انسان	موش
آنتره	10013	15185
آنسامبل	ENSG00000094631	ENSMUSG00000031161
UniProt	Q9UBN7	Q9Z2V5
RefSeq (mRNA)	NM_006044.2	NM_001130416.1
RefSeq (protein)	NP_006035.2	NP_001123888.1
موقعیت (UCSC)	Chr X: 48.66 – 48.68 Mb	Chr X: 7.93 – 7.95 Mb
جستجوی پاب‌مد	[۱]	[۲]